ABCD1

ATP binding cassette subfamily D member 1

Ensembl:: ENSG00000101986
UniProt:: P33897
OMIM:: 300371
Synonyms:: ADRENOLEUKODYSTROPHY, ALD, ALDP, AMN

Cilia effects upon perturbation of ABCD1

Ciliogenesis screen results (4 screens)

Kim2016: Not Reported
Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia associated gene

Functional category

Ciliary assembly/disassembly
Metabolism

Function

Strikingly, disruption of additional peroxisomal β-oxidation-related genes, including ABCD1, ACOX1, TYSND1, and HSD17B4, markedly impaired primary ciliogenesis under serum deprivation conditions(40102401).

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