ABLIM3

actin binding LIM protein family member 3

Tier: Cilia-Associated Genes

Ensembl:: ENSG00000173210
UniProt:: O94929
OMIM:: 611305
Synonyms:: KIAA0843

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: decreased exploration in new environment, increased hematocrit, increased freezing behavior, increased lymphocyte cell number, decreased basophil cell number, enlarged lymph nodes, decreased body length, anophthalmia

Subcellular localization

No ciliary localization reported (cilia-associated gene).

References: PMID:22684256

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation

Function

Involved in ciliation-related actin dynamics and LR patterning (22684256)

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