ACOT13

acyl-CoA thioesterase 13

Tier: Cilia-Associated Genes

Ensembl:: ENSG00000112304
UniProt:: Q9NPJ3
OMIM:: 615652
Synonyms:: HT012, THEM2

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

mitochondria, nucleus

Functional category

Ciliary assembly/disassembly
Signaling (Hedgehog, GPCRs, ion channels)

Function

Through integrating PPI and gene expression analyses, acyl-CoA thioesterase 13 (ACOT13), which has not been reported to be related to autosomal dominant polycystic kidney disease (ADPKD), and prostaglandin E receptor 2 (PTGER2) were identified as potential genes associated with ADPKD(PMID: 34886911).

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