ACOT7

acyl-CoA thioesterase 7

Ensembl:: ENSG00000097021
UniProt:: O00154
OMIM:: 602587
Synonyms:: ACH1, ACT, BACH, CTE-II, HBACH

Cilia effects upon perturbation of ACOT7

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-10.92) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia associated gene

Functional category

Ciliary assembly/disassembly
Cardiac & muscle development

Function

Presence of primary cilia is also validated using immunofluorescence in the stroma and muscle cells of the mouse colon, using known markers of the primary cilia. Acot7 is identified as a primary cilium associated marker and found to be expressed in myenteric ganglia.

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