ADAM32

ADAM metallopeptidase domain 32

Ensembl:: ENSG00000275594, ENSG00000197140
UniProt:: Q8TC27
OMIM:: 618602

Cilia effects upon perturbation of ADAM32

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: decreased bone mineral density, decreased lean body mass, increased total body fat amount, decreased bone mineral content, impaired pupillary reflex

Subcellular localization

flagella, lysosomes

Function

ADAM32 has localized in flagella.

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