ADAM32

ADAM metallopeptidase domain 32

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000275594
UniProt:: Q8TC27
OMIM:: 618602

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: decreased bone mineral density, decreased lean body mass, increased total body fat amount, decreased bone mineral content, impaired pupillary reflex

Subcellular localization

flagella, lysosomes

References: Human Protein Atlas, PMID:25613900

Function

ADAM32 has localized in flagella.

Note: Additional interactive sections (perturbation matrix visualization, phylogenetic conservation strip, protein complex network, STRING interactions) require JavaScript. Browse CiliaHub for the full experience.