ADRB3

adrenoceptor beta 3

Ensembl:
ENSG00000188778
UniProt:
P13945
OMIM:
109691

Cilia effects upon perturbation of ADRB3

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
increased cd4-negative, cd25-positive nk t cell number
Human ciliopathy phenotype:
sinusitis; obesity

Subcellular localization

basal body, nucleus

Functional category

  • Ciliary assembly/disassembly
  • T cell biology
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

ADRB3 has localized in basal body.