AGR3

anterior gradient 3, protein disulphide isomerase family member

Tier: Cilia-Associated Genes

Ensembl:
ENSG00000173467
UniProt:
Q8TD06
OMIM:
609482
Synonyms:
BCMP11, HAG-3, HAG3, PDIA18

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

rootlet

References: PMID:25751668, PMID:42010243

Functional category

  • Ciliary assembly/disassembly

Function

AGR3 expression is restricted to ciliated cells in the airway epithelium. Required for Regulation of Ciliary Beat Frequency in the Airway(25751668).