AKTIP

AKT interacting protein

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000166971
UniProt:
Q9H8T0
OMIM:
608483
Synonyms:
FLJ13258, FTS

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-7.67) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
decreased bone mineral density, hyperactivity, abnormal gait, decreased bone mineral content

Subcellular localization

cilia, basal body

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation

Function

AKTIP has localized in cilia.