AKTIP
AKT interacting protein
- Ensembl:
- ENSG00000166971
- UniProt:
- Q9H8T0
- OMIM:
- 608483
- Synonyms:
- FLJ13258, FTS
Cilia effects upon perturbation of AKTIP
Ciliogenesis screen results (3 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-7.67) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- decreased bone mineral density, hyperactivity, abnormal gait, decreased bone mineral content
- Mouse ciliopathy phenotype:
- abnormal reti morphology, increased circulating aspartate transamise level
Subcellular localization
cilia
Functional category
- Ciliary assembly/disassembly
- Actin & cytoskeleton regulation
Function
AKTIP has localized in cilia.