ANKRD45

Cilia effects upon perturbation of ANKRD45

Loss-of-function effect:

No effect

Ciliogenesis screen results (1 screen)

• Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:

hyperactivity

Subcellular localization

basal body

Functional category

• Ciliary assembly/disassembly

Function

The expression pattern of ankrd45 in early zebrafish embryos was tissue specific with high enrichment in ciliated organs, suggesting that Ankrd45 possibly plays a role during cilia development (31208154). Mtmr11 and Ankrd45 are similarly uncharacterized and were found specifically at basal bodies(29180514).