ANKRD55
ankyrin repeat domain 55
- Ensembl:
- ENSG00000164512
- UniProt:
- Q3KP44
- OMIM:
- 615189
- Synonyms:
- FLJ11795
Cilia effects upon perturbation of ANKRD55
- Cilia number / % ciliated:
- Decreased cilia number
- Loss-of-function effect:
- Shorter cilia
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.47) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Subcellular localization
basal body
Functional category
- Ciliary assembly/disassembly
Function
ANKRD55 is a new component of the intraflagellar transport (IFT) particle, is important for ciliogenesis, and has a role in neural tube closure (28596423). ANKRD55 was detected at the basal body in ciliated cells.