ANKS3

ankyrin repeat and sterile alpha motif domain containing 3

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000168096
UniProt:: Q6ZW76
OMIM:: 617310
Synonyms:: FLJ32345, FLJ32767, KIAA1977

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: preweaning lethality, complete penetrance

Subcellular localization

cilia

References: PMID:26327442

Functional category

Ciliary assembly/disassembly

Function

Interacts with ANKS6 through sterile alpha motif (SAM), localised to renal cilia in mice

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