ANO3

anoctamin 3

Ensembl:: ENSG00000134343
UniProt:: Q9BYT9
OMIM:: 610110
Synonyms:: C11ORF25, DYT23, GENX-3947, TMEM16C

Cilia effects upon perturbation of ANO3

Loss-of-function effect:: Longer cilia

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: decreased circulating alanine transamise level

Subcellular localization

cilia

Functional category

Ciliary assembly/disassembly
Viral interactions
Signaling (Hedgehog, GPCRs, ion channels)

Function

The calcium-dependent regulator of potassium channels ANO3 localized in cilia.

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