ANXA5

annexin A5

Ensembl:
ENSG00000164111
UniProt:
P08758
OMIM:
131230
Synonyms:
ANX5, CPB-I, ENX2, PAP-I, RPRGL3

Cilia effects upon perturbation of ANXA5

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Pusapati et al. 2018 (CRISPR) [CRISPR]: Positive Regulator (Hh signaling, neg_rank=959, lfc=-1.68) PMID:30270045

Subcellular localization

autophagosomes, cilia, endosome

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation

Function

In frog olfactory epithelia, ANXA isoforms 1, 2, and 5 bind to dicalcin in a Ca2+-dependent manner (17714509). ANXA5 up-regulated in mouse OE pulse-exposed to the odorant octa l (18336002). ANXA1, ANXA2, ANXA5, S100A5, PMCA1, and NCKX4 in the cilia of mouse OSNs (24748648). ANXA1, ANXA2, ANXA5, S100A5, PMCA1, and NCKX4 in the cilia of mouse OSNs (24748648).