ANXA6

annexin A6

Ensembl:
ENSG00000197043
UniProt:
P08133
OMIM:
114070
Synonyms:
ANX6

Cilia effects upon perturbation of ANXA6

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
abnormal eye size, increased lean body mass, increased bone mineral content, abnormal vibrissa morphology, decreased circulating cholesterol level, decreased circulating ldl cholesterol level

Subcellular localization

basal body, transition zone

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Cardiac & muscle development
  • Muscle contraction & physiology
  • Transition zone

Function

ANXA6 has localized in basal body, transition zone.