ANXA6

annexin A6

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000197043
UniProt:
P08133
OMIM:
114070
Synonyms:
ANX6

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
abnormal eye size, increased lean body mass, increased bone mineral content, abnormal vibrissa morphology, decreased circulating cholesterol level, decreased circulating ldl cholesterol level

Subcellular localization

basal body, transition zone

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Cardiac & muscle development
  • Muscle contraction & physiology
  • Transition zone

Function

ANXA6 has localized in basal body, transition zone.