AQP5

aquaporin 5

Ensembl:
ENSG00000161798
UniProt:
P55064
OMIM:
600442

Cilia effects upon perturbation of AQP5

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.18) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation

Function

In oviduct, AQP1, AQP3, AQP6, and AQP9 were strongly expressed especially in ciliated columnar epithelial cells (Fig. 4). Immunoreactivities of AQP1, AQP3, AQP6, and AQP9 were localized mainly to cilia and luminal surface of epithelial cells with a subtle subtype-specific difference. (33110949).