AQP9

aquaporin 9

Ensembl:
ENSG00000103569
UniProt:
O43315
OMIM:
602914
Synonyms:
HST17287, SSC1

Cilia effects upon perturbation of AQP9

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
abnormal tibia morphology, abnormal cholesterol homeostasis
Mouse ciliopathy phenotype:
abnormal auditory brainstem response, short tibia

Subcellular localization

cilia

Functional category

  • Ciliary assembly/disassembly

Function

In oviduct, AQP1, AQP3, AQP6, and AQP9 were strongly expressed especially in ciliated columnar epithelial cells (Fig. 4). Immunoreactivities of AQP1, AQP3, AQP6, and AQP9 were localized mainly to cilia and luminal surface of epithelial cells with a subtle subtype-specific difference. (33110949).