ARHGAP36
Rho GTPase activating protein 36
- Ensembl:
- ENSG00000147256
- UniProt:
- Q6ZRI8
- OMIM:
- 300937
- Synonyms:
- FLJ30058
Cilia effects upon perturbation of ARHGAP36
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Ciliopathy associations
- Bazex-Dupré-Christol Syndrome
Subcellular localization
basal body, cytosol
Functional category
- Ciliary assembly/disassembly
- Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
- Signaling (Hedgehog, GPCRs, ion channels)
Function
Patched1-ArhGAP36-PKA- Inversin axis determines the ciliary translocation of Smoothened for Sonic Hedgehog pathway activation(30598432).