ARMC8

armadillo repeat containing 8

Ensembl:: ENSG00000114098
UniProt:: Q8IUR7
OMIM:: 618521
Synonyms:: DKFZP434A043, GID5, HSPC056, VID28

Cilia effects upon perturbation of ARMC8

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.16) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia

Functional category

Ciliary assembly/disassembly

Function

RMND5A and TWA1 are present at the basal body, at the axoneme in primary cilia and motile mono-cilia, and at the centrioles in cycling cells, and other integral components of the GID complex(ARMC8 and MKLN1) are present at the axoneme in primary cilia, suggesting that the GID complex has a function at the primary cilium(35543155).

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