ATP1A4

ATPase Na+/K+ transporting subunit alpha 4

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000132681
UniProt:
Q13733
OMIM:
607321
Synonyms:
ATP1AL2

Ciliogenesis screen results (3 screens)

  • Kim2016: Not Reported
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

flagella

References: PMID:20826726

Functional category

  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Actin & cytoskeleton regulation
  • Metabolism
  • Reproduction & sperm
  • Viral interactions
  • Cell migration & adhesion
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

Rat Atp1a4 transgene is expressed in mouse spermatozoa and that it is localized to the sperm flagellum(20826726).