ATXN1
ataxin 1
- Ensembl:
- ENSG00000124788
- UniProt:
- P54253
- OMIM:
- 601556
- Synonyms:
- ATX1, D6S504E, SCA1
Cilia effects upon perturbation of ATXN1
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-16.58) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Phenotypes
- Human ciliopathy phenotype:
- spinocerebellar ataxia type 1
Subcellular localization
cilia associated gene, nucleus
Functional category
- Ciliary assembly/disassembly
Function
Mutations in the ATXN1 gene cause Spinocerebellar Ataxia (PMID: 17190598).