AXIN1

axin 1

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000103126
UniProt:
O15169
OMIM:
603816
Synonyms:
PPP1R49

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia, cytosol, nucleus, ciliary tip, transition zone

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Transcription regulation

Function

AXIN1 has localized in primary cilia.