BMAL1

basic helix-loop-helix ARNT like 1

Tier: Cilia-Associated Genes

Ensembl:
ENSG00000133794
OMIM:
602550
Synonyms:
ARNTL, ARNTL1, BHLHE5, JAP3, MOP3, PASD3

Subcellular localization

No ciliary localization reported (cilia-associated gene).

References: PMID:37971148

Functional category

  • Non-motile cilium / primary cilium

Function

The circadian rhythm of primary cilium length was abolished in Bmal1‐KO cells, and the length of primary cilia was always the same as that of the WT cells at the time of the maximum length (40–44 h after synchronization). This result suggests that Bmal1 itself could function in an inhibitory manner on the formation of primary cilia(37971148).