BMAL1
basic helix-loop-helix ARNT like 1
Tier: Cilia-Associated Genes
- Ensembl:
- ENSG00000133794
- OMIM:
- 602550
- Synonyms:
- ARNTL, ARNTL1, BHLHE5, JAP3, MOP3, PASD3
Subcellular localization
No ciliary localization reported (cilia-associated gene).
References: PMID:37971148
Functional category
- Non-motile cilium / primary cilium
Function
The circadian rhythm of primary cilium length was abolished in Bmal1‐KO cells, and the length of primary cilia was always the same as that of the WT cells at the time of the maximum length (40–44 h after synchronization). This result suggests that Bmal1 itself could function in an inhibitory manner on the formation of primary cilia(37971148).