CABCOCO1

ciliary associated calcium binding coiled-coil 1

Ensembl:: ENSG00000183346
UniProt:: Q8IVU9
Synonyms:: ARIEL, BA63A2.1, C10ORF107, EM:AC022398.2, MGC44593

Cilia effects upon perturbation of CABCOCO1

Phenotypes

Mouse ciliopathy phenotype:: increased circulating aspartate transamise level, male infertility, increased circulating alanine transamise level

Subcellular localization

basal body, flagella

Functional category

Ciliary assembly/disassembly
Reproduction & sperm

Function

CABCOCO1 is involved in the control of sperm flagellar movement (26990073).

Model organism evidence

Mus musculus (2 references)

CCDC189 affects sperm flagellum formation by interacting with CABCOCO1.

CABCOCO1, a novel coiled-coil protein With calcium-binding activity, is localized in the sperm flagellum.

PMIDs: 37601242, 26990073

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