CABP4

calcium binding protein 4

Ensembl:: ENSG00000175544
UniProt:: P57796
OMIM:: 608965
Synonyms:: CSNB2B

Cilia effects upon perturbation of CABP4

Ciliogenesis screen results (4 screens)

Kim2016: Not Reported
Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: hydrocephaly; hyperactivity; abnormal brain morphology

Subcellular localization

axoneme

Functional category

Non-motile cilium / primary cilium

Function

The localization of CaBP4 at the ciliary axoneme suggests that CaBP4 is involved in the trafficking of signal transduction proteins and/or structural components of outer segments (https://grantome.com/grant/NIH/R03-EY014561-03).

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