CACNA2D3

calcium voltage-gated channel auxiliary subunit alpha2delta 3

Ensembl:
ENSG00000157445
UniProt:
Q8IZS8
OMIM:
606399
Synonyms:
ALPHA2DELTA-3, HSA272268

Cilia effects upon perturbation of CACNA2D3

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
decreased circulating triglyceride level, increased circulating sodium level, decreased circulating free fatty acids level, decreased circulating glucose level

Subcellular localization

flagella

Functional category

  • Signaling (Hedgehog, GPCRs, ion channels)

Function

CACNA2D3 has localized in flagella.