CAMK1D

calcium/calmodulin dependent protein kinase ID

Ensembl:: ENSG00000183049
UniProt:: Q8IU85
OMIM:: 607957
Synonyms:: CKLIK

Cilia effects upon perturbation of CAMK1D

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: decreased exploration in new environment, hyperplasia, enlarged spleen, increased total body fat amount, increased grip strength, abnormal spleen morphology, decreased heart weight, abnormal eye morphology, decreased lean body mass, decreased bone mineral density, increased blood urea nitrogen level, enlarged pancreas
Mouse ciliopathy phenotype:: hydrometra, abnormal liver morphology

Subcellular localization

basal body, nucleus, transition zone

Functional category

Ciliary assembly/disassembly
Transition zone
Transcription regulation

Function

CAMK1D has localized in basal body, transition zone.

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