CAMK2D

calcium/calmodulin dependent protein kinase II delta

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000145349
UniProt:
Q13557
OMIM:
607708
Synonyms:
CAMKD

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.38) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia, cytosol, nucleus, transition zone, ciliary tip

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Actin & cytoskeleton regulation
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Cardiac & muscle development
  • Muscle contraction & physiology
  • Transition zone
  • Transcription regulation

Function

CAMK2D has localized in transition zone, ciliary tip.