CATSPERD

cation channel sperm associated auxiliary subunit delta

Ensembl:: ENSG00000174898
UniProt:: Q86XM0
OMIM:: 617490
Synonyms:: MGC39581, TMEM146

Cilia effects upon perturbation of CATSPERD

Ciliogenesis screen results (2 screens)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Pusapati et al. 2018 (CRISPR) [CRISPR]: Negative Regulator (Hh signaling, pos_rank=465, lfc=0.57) PMID:30270045

Subcellular localization

flagella, lysosomes

Functional category

Actin & cytoskeleton regulation
T cell biology
Reproduction & sperm
Protein processing & maturation
Cell migration & adhesion
Signaling (Hedgehog, GPCRs, ion channels)

Function

CATSPERδ is an essential element of the CATSPER channel complex and propose that CATSPERδ is required for proper CATSPER channel assembly and/or transport (21224844).

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