CATSPERZ

catsper channel auxiliary subunit zeta

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000219435
UniProt:: Q9NTU4
OMIM:: 617511
Synonyms:: C11ORF20, DKFZP566E164, TEX40

Phenotypes

Mouse phenotype:: decreased grip strength, impaired righting response, mydriasis, limb grasping, decreased bone mineral density, decreased bone mineral content

Subcellular localization

flagella, ciliary tip

References: PMID:41005307, PMID:28226241

Functional category

Actin & cytoskeleton regulation
Reproduction & sperm
Protein processing & maturation
Cell migration & adhesion
Signaling (Hedgehog, GPCRs, ion channels)

Function

In both human and mouse sperm cells, CatSper ε and ζ proteins are localized to the principal piece of the tails (28226241).

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