CCDC148

coiled-coil domain containing 148

Ensembl:: ENSG00000153237
UniProt:: Q8NFR7
Synonyms:: MGC125588

Cilia effects upon perturbation of CCDC148

Ciliogenesis screen results (1 screen)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: increased vertical activity

Subcellular localization

basal body

Functional category

Ciliary assembly/disassembly

Function

Ccdc148 specifically localized at the proximal region of Centrin-decorated CPF and was complementary to the Cep131-enriched distal region(39165107).

Model organism evidence

Mus musculus (1 reference)

However, the mechanism by which the CP is upheld above the transition zone (TZ) remains unclear.

PMIDs: 39165107

Note: Additional interactive sections (perturbation matrix visualization, phylogenetic conservation strip, protein complex network, STRING interactions) require JavaScript. Browse CiliaHub for the full experience.