CCDC149

coiled-coil domain containing 149

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000181982
UniProt:
Q6ZUS6
Synonyms:
DKFZP761B107

Ciliogenesis screen results (2 screens)

  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Pusapati et al. 2018 (CRISPR) [CRISPR]: Positive Regulator (Hh signaling, neg_rank=890, lfc=-1.31) PMID:30270045

Subcellular localization

basal body

References: PMID:27930654

Functional category

  • Ciliary assembly/disassembly

Function

CCDC-149 are observed at the amphid/phasmid basal bodies in Caenorhabditis elegans (PMID: 27930654).