CCDC170

coiled-coil domain containing 170

Ensembl:: ENSG00000120262
UniProt:: Q8IYT3
Synonyms:: BA282P11.1, C6ORF97, FLJ23305

Cilia effects upon perturbation of CCDC170

Ciliogenesis screen results (1 screen)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: abnormal vocalization

Subcellular localization

cilia associated gene

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
T cell biology

Function

Gene sets (GS) associated with ependymal development, ciliary function and the immune system were specially modified qPCR confirmed reduced expression in the KO mice genes and these genes associated with ciliary assembly (Cfap43, Cfap69 and Ccdc170)( 38956598).

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