CCDC183
coiled-coil domain containing 183
- Ensembl:
- ENSG00000213213
- UniProt:
- Q5T5S1
- OMIM:
- 615955
- Synonyms:
- BA216L13.7, KIAA1984, MGC15438
Cilia effects upon perturbation of CCDC183
Ciliogenesis screen results (1 screen)
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Phenotypes
- Mouse phenotype:
- process of degenerative change, increased neutrophil cell number, abnormal skin morphology, increased hemoglobin content, increased erythrocyte cell number
Subcellular localization
basal body, transition zone
Functional category
- Ciliary assembly/disassembly
- Transition zone
Function
CCDC183 has localized in basal body, transition zone.
Model organism evidence
Mus musculus (1 reference)
CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility.
PMIDs: 37882665