CCDC188

coiled-coil domain containing 188

Ensembl:
ENSG00000234409
UniProt:
H7C350

Cilia effects upon perturbation of CCDC188

Loss-of-function effect:
Shorter Sperm Tail

Ciliogenesis screen results (1 screen)

  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

basal body, flagella

Functional category

  • Ciliary assembly/disassembly
  • Reproduction & sperm

Function

CCDC188 has localized in basal body,flagella. Sperm tails from Ccdc188 KO mice were significantly shorter than those from control males (PMID: 39292630)