CCDC34
coiled-coil domain containing 34
- Ensembl:
- ENSG00000109881
- UniProt:
- Q96HJ3
- OMIM:
- 612324
- Synonyms:
- L15, NY-REN-41, RAMA3
Cilia effects upon perturbation of CCDC34
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-11.97) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Phenotypes
- Mouse phenotype:
- abnormal optic disk morphology
- Mouse ciliopathy phenotype:
- male infertility
Subcellular localization
flagella, lysosomes
Functional category
- Reproduction & sperm
Function
CCDC34 has localized in flagella.