CCDC38

coiled-coil domain containing 38

Ensembl:
ENSG00000165972
UniProt:
Q502W7
Synonyms:
FLJ40089

Cilia effects upon perturbation of CCDC38

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

basal body

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • T cell biology
  • Reproduction & sperm
  • Cell migration & adhesion

Function

CCDC113, CCDC96, C4orf47, CCDC38, C7orf31, CCDC146, CCDC81 and CCDC116 as centrosome-associated proteins(25074808).

Model organism evidence

Mus musculus (1 reference)

CCDC38 is required for sperm flagellum biogenesis and male fertility in mice.

PMIDs: 35587122