CCNL2

cyclin L2

Ensembl:
ENSG00000221978
UniProt:
Q96S94
OMIM:
613482
Synonyms:
ANIA-6B, CCNM, CCNS, HLA-ISO, PCEE

Cilia effects upon perturbation of CCNL2

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: Positive Regulator (Hh signaling, casTLE effect=-0.74) PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, nucleus

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation

Function

CCNL2 has localized in basal body.