CCT7

chaperonin containing TCP1 subunit 7

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000135624
OMIM:: 605140
Synonyms:: CCTH, NIP7-1

Subcellular localization

flagella, Cytosol

References: PMID:39743588

Functional category

Ciliary assembly/disassembly

Function

CCT7 components of the chaperonin-containing TCP1 (CCT/TRiC complex), associated mainly with sperm flagella assembly, not specific to cilia structure(39743588). Identified by cryo-EM as a component of the radial spoke-associated barrel in sperm flagella (Leung et al., 2025, Nature, PMID 39743588).

Note: Additional interactive sections (perturbation matrix visualization, phylogenetic conservation strip, protein complex network, STRING interactions) require JavaScript. Browse CiliaHub for the full experience.