CD81

CD81 molecule

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000110651
UniProt:
P60033
OMIM:
186845
Synonyms:
S5.7, TAPA-1, TAPA1, TSPAN28

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-12.24) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia, lysosomes

References: PMID:26585297

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Viral interactions
  • Cell migration & adhesion
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Cardiac & muscle development

Function

CD81 and CD82 localized in cilia (26585297).