CD9

CD9 molecule

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000010278
UniProt:
P21926
OMIM:
143030
Synonyms:
BA2, MIC3, MRP-1, P24, TSPAN29

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia

References: PMID:35316373

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Viral interactions
  • Cell migration & adhesion
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Cardiac & muscle development

Function

The extracellular vesicle (EV) marker TSP-6(an ortholog of mammalian CD9) localizes to the cilia region(34533135). The cells of the MCL on the IL side consisted of cluster of differentiation 9 (CD9)-positive stem/progenitor cells with or without motile cilia(35316373).