CDK18

cyclin dependent kinase 18

Ensembl:
ENSG00000117266
UniProt:
Q07002
OMIM:
169190
Synonyms:
PCTAIRE3, PCTK3

Cilia effects upon perturbation of CDK18

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-7.70) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse ciliopathy phenotype:
increased circulating creatinine level

Subcellular localization

basal body, cilia

Functional category

  • Ciliary assembly/disassembly

Function

CDK18 has localized in basal body, cilia.