CDS1

CDP-diacylglycerol synthase 1

Ensembl:
ENSG00000163624
UniProt:
Q92903
OMIM:
603548

Cilia effects upon perturbation of CDS1

Ciliogenesis screen results (4 screens)

  • Kim2016: No effect
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.56) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia

Function

CDS1 has located to motile cilia.

Model organism evidence

Mus musculus (1 reference)

This study aimed to elucidate the pathogenic mechanism linking CFAP251 deficiency to human male infertility and to determine whether CFAP251 plays an active role in both flagella and cilia across species.

PMIDs: 41943837