CEP126

centrosomal protein 126

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000110318
UniProt:: Q9P2H0
OMIM:: 614634
Synonyms:: KIAA1377

Ciliogenesis screen results (1 screens)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: impaired pupillary reflex, increased fasting circulating glucose level

Subcellular localization

basal body

References: PMID:24867236

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation

Function

Cep126 localised to the centrosome in a microtubule-independent manner and CEP126 is a regulator of microtubule organisation at the centrosome that acts through modulation of the transport of pericentriolar satellites, and consequently, of the organisation of cell structure(24867236).

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