CEP20

centrosomal protein 20

Ensembl:: ENSG00000276914, ENSG00000133393
UniProt:: Q96NB1
OMIM:: 617149
Synonyms:: C16ORF63, DKFZP686N1651, FLJ31153, FOPNL, FOR20

Cilia effects upon perturbation of CEP20

Cilia number / % ciliated:: Decreased cilia number
Loss-of-function effect:: Shorter cilia

Subcellular localization

basal body

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Cilia length regulation

Function

Regulation of integrity of the centriole distal end and membrane anchoring. Complex with OFD1 to initiate ciliogenesis and control cilia length (26643951). Involved in cilia formation and regulating the interaction of PCM1 satellites with and motors (20551181). Regulates the assembly and maintains the stability and dy mics of . It may inhibit tubulin assembly by sequestering soluble tubulin (28694353).

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