CERS5

ceramide synthase 5

Ensembl:: ENSG00000139624
UniProt:: Q8N5B7
OMIM:: 615335
Synonyms:: FLJ25304, LASS5, MGC45411, TRH4

Cilia effects upon perturbation of CERS5

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: abnormal motor coordition/balance, increased circulating sodium level, decreased exploration in new environment, decreased bone mineral density, decreased bone mineral content, decreased thigmotaxis, abnormal bone structure

Subcellular localization

cilia, nucleus

Functional category

Ciliary assembly/disassembly

Function

CERS5 has localized in ciliary tip, primary cilia.

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