CFAP161

cilia and flagella associated protein 161

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000156206
UniProt:: Q6P656
Synonyms:: C15ORF26, FLJ38615

Ciliogenesis screen results (1 screens)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: decreased total body fat amount, enlarged spleen, abnormal thyroid gland morphology, abnormal mouth morphology, abnormal spleen morphology, abnormal mammary gland morphology, enlarged thyroid gland

Subcellular localization

basal body, cilia

References: PMID:42010243, PMID:25139857, PMID:24094744

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Reproduction & sperm
Cell migration & adhesion

Function

Also called C15orf26. Studies in zebrafish suggest it is essential for cilia motility (24094744)

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