CFAP97D1

CFAP97 domain containing 1

Ensembl:: ENSG00000231256
UniProt:: B2RV13
OMIM:: 619866
Synonyms:: C17ORF105

Cilia effects upon perturbation of CFAP97D1

Phenotypes

Mouse phenotype:: decreased prepulse inhibition
Mouse ciliopathy phenotype:: abnormal reti blood vessel morphology

Subcellular localization

cilia, flagella

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
T cell biology
Reproduction & sperm
Cell migration & adhesion

Function

Cfap97d1 is required for sperm flagellum ultra-structure mainte nce, thereby playing a critical role in sperm function and male fertility in mice (32785227).

Model organism evidence

Mus musculus (1 reference)

Cfap97d1 is important for flagellar axoneme maintenance and male mouse fertility.

PMIDs: 32785227

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