CKAP2

cytoskeleton associated protein 2

Ensembl:
ENSG00000136108
UniProt:
Q8WWK9
OMIM:
611569
Synonyms:
FLJ10749, LB1, SE20-10, TMAP

Cilia effects upon perturbation of CKAP2

Cilia number / % ciliated:
No effect
Loss-of-function effect:
No effect

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Kim et al. 2010 (siRNA) [siRNA]: Longer Cilia (Area per Cilia z=2.50) PMID:20393562

Subcellular localization

centrosome, cilia

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation

Function

CKAP2, where localization to the cilium and part of the microtubule cytoskeleton were seen in some cells, and localization to vesicles in other cells (PMID: 40654709).