CLEC3B

C-type lectin domain family 3 member B

Ensembl:
ENSG00000163815
UniProt:
P05452
OMIM:
187520
Synonyms:
TN, TNA

Cilia effects upon perturbation of CLEC3B

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-12.52) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Pusapati et al. 2018 (CRISPR) [CRISPR]: Positive Regulator (Hh signaling, neg_rank=389, lfc=-0.76) PMID:30270045

Phenotypes

Mouse phenotype:
decreased grip strength

Ciliopathy associations

  • Retinal Dystrophy/Degeneration

Subcellular localization

cilia associated gene

Function

GOBP enrichment items indicated that the high expression of the CLEC3B gene was related to the cilium movement signaling pathway (PMID: 35936688).