CLIC4

chloride intracellular channel 4

Ensembl:
ENSG00000169504
UniProt:
Q9Y696
OMIM:
606536
Synonyms:
CLIC4L, DKFZP566G223, H1, HUH1, P64H1

Cilia effects upon perturbation of CLIC4

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.36) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

centrosome, cytosol, flagella, nucleus

Functional category

  • Actin & cytoskeleton regulation
  • Cell migration & adhesion
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

CLIC4 has localized in flagella.